The direct healthcare professional communication (DHPC) is a communication intervention by which important safety information is delivered directly to individual healthcare professionals (HCPs), alerting them to take certain actions to ensure the safe and effective use of medicines.

As DHPC plays a critical role in pharmacovigilance, it is important to understand how effective it is at alerting HCPs to important safety issues. DHPC effectiveness is a debatable topic among regulatory professionals, and findings from the little published research are inconclusive.